disease has basis in disruption of disease caused by disruption of disease has feature disease has major feature nuclear receptor activity Abnormal thyroid-stimulating hormone level thyroid hormone resistance syndrome https://www.malacards.org/card/thyroid_hormone_resistance_syndrome RTH MESH:D018382 DOID:11633 UMLS:C2940786 ICD9:259.8 SCTID:111567006 MONDO:0001328 NANDO:2100121 MEDGEN:424854 GARD:0022922 An inherited autosomal recessive trait, characterized by peripheral resistance to thyroid hormones and the resulting elevation in serum levels of thyroxine and triiodothyronine. NANDO:1200395 generalised thyroid hormone resistance NANDO:2200341 hyperthyroxinemia hypothyroidism inherited thyroid metabolism disease