<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0001422"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/mondo#">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#excluded_subClassOf"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0004021 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004021">
        <rdfs:label>disease has basis in disruption of</rdfs:label>
        <rdfs:label>disease caused by disruption of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0004029 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004029">
        <rdfs:label>disease has feature</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/GO_0035932 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0035932">
        <rdfs:label>aldosterone secretion</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0003351 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0003351">
        <rdfs:label>Decreased circulating renin concentration</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0030852 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0030852">
        <rdfs:label>High pulse pressure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0001422 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0001422">
        <rdfs:label>primary aldosteronism</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0003009"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0003351"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0030852"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004021"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/GO_0035932"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns5:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/9097</ns5:IAO_0000233>
        <ns3:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/conns_syndrome</ns3:curated_content_resource>
        <oboInOwl:hasExactSynonym>Conn&#39;s syndrome</oboInOwl:hasExactSynonym>
        <ns5:IAO_0000115>An endocrine disorder characterized by excessive production of aldosterone by the adrenal glands. Causes include adrenal gland adenoma and adrenal gland hyperplasia. The overproduction of aldosterone results in sodium and water retention and hypokalemia. Patients present with high blood pressure, muscle weakness, and headache.</ns5:IAO_0000115>
        <oboInOwl:hasDbXref>NANDO:2200361</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:E26.0</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Conn syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>primary aldosteronism</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>icd11.foundation:197924221</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:E26.01</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>primary hyperaldosteronism</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>ICD9:255.12</oboInOwl:hasDbXref>
        <rdfs:comment>Editor note: DOID class refers to adenoma-caused Conn syndrome</rdfs:comment>
        <oboInOwl:hasDbXref>SCTID:190507007</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C34510</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1384514</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DOID:12028</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0001422</oboInOwl:id>
        <oboInOwl:hasDbXref>MEDGEN:278002</oboInOwl:hasDbXref>
        <skos:exactMatch rdf:resource="http://id.who.int/icd/entity/197924221"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/278002"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/190507007"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C1384514"/>
        <skos:exactMatch rdf:resource="http://purl.bioontology.org/ontology/ICD10CM/E26.0"/>
        <skos:exactMatch rdf:resource="http://purl.bioontology.org/ontology/ICD10CM/E26.01"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_12028"/>
        <ns3:excluded_subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0003924"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C34510"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0003009 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0003009">
        <rdfs:label>hyperaldosteronism</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0003924 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0003924">
        <rdfs:label>adrenal cortex adenoma</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



