disease has major feature Hyperparathyroidism parathyroid gland disorder hyperparathyroidism https://www.malacards.org/card/hyperparathyroidism UMLS:C0020502 NANDO:2100123 MEDGEN:6967 ICD9:252.00 DOID:13543 NCIT:C48259 MESH:D006961 EFO:0008506 Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It may be primary or secondary; primary hyperparathyroidism is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. Secondary hyperparathyroidism is caused by the chronic stimulation of the parathyroid glands in patients with chronic renal failure, rickets, and malabsorption syndromes. SCTID:66999008 MONDO:0001741 icd11.foundation:9633776 NANDO:2200343 hyperparathyroidism ICD9:252.0