disease has feature Abnormality of the nervous system Hypotension commensal bacterial infectious disease toxic shock syndrome https://www.malacards.org/card/toxic_shock_syndrome bacterial TSS ICD9:040.82 bacterial toxic-shock syndrome DOID:14115 toxic shock syndrome, (TSS) GARD:0009560 MEDGEN:109414 MESH:D012772 ICD10CM:A48.3 TSS, toxic shock syndrome MONDO:0001881 SCTID:18504008 A rare acute life-threatening systemic bacterial noncontagious illness caused by exotoxins from bacteria of either the Streptococcus pyogenes or Staphylococcus aureus type. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. TSS syndrome (TSS), toxic shock UMLS:C0600327 NORD:1782 Orphanet:36234 NCIT:C35498 shock syndrome (TSS), toxic icd11.foundation:114886962 toxic shock syndrome staphylococcal toxic shock syndrome syndromic disease