disease arises from feature disease has basis in feature Richter transformation https://github.com/monarch-initiative/mondo/issues/9758 https://www.malacards.org/card/richters_syndrome NCIT:C35424 MONDO:0002083 SCTID:277550009 chronic lymphocytic leukemia/small lymphocytic lymphoma with Richter transformation Richter's syndrome chronic lymphocytic leukemia with Richter transformation Transformation of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) into a more aggressive type of lymphoma, usually diffuse large B-cell lymphoma (immunoblastic or centroblastic variant). Occasional cases of transformation to Hodgkin's lymphoma have also been described, particularly in patients treated with purine nucleotide analogs. Molecular genetic studies suggest that in approximately half of the cases, the lymphoma is clonally related to the underlying CLL/SLL, whereas in the remaining cases the lymphoma probably represents a secondary, unrelated neoplasm. icd11.foundation:1736108343 MEDGEN:91159 DOID:1703 Richter's transformation Richter syndrome GARD:0007578 UMLS:C0349631 chronic lymphocytic leukemia/small lymphocytic lymphoma neoplastic syndrome secondary neoplasm