preretinal fibrosis https://www.malacards.org/card/preretinal_fibrosis ICD9:362.56 ICD9:362.89 MEDGEN:87388 DOID:2006 macular puckering of retina A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) retinal pigment epithelial cells. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the fovea centralis. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with retinal holes, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291) SCTID:367649002 MONDO:0002174 UMLS:C0339543 MESH:D019773 degeneration of macula and posterior pole