<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0002211"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/mondo#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#rare"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0004026 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004026">
        <rdfs:label>disease has location</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000236 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000236">
        <rdfs:label>B cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002211 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002211">
        <rdfs:label>B cell deficiency</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0003778"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0004805"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0021094"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004026"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000236"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/b_cell_deficiency</ns5:curated_content_resource>
        <oboInOwl:hasDbXref>GARD:0023084</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DOID:2115</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C4799</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C1855067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:279.03</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>B-cell deficiency</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>immunoglobulin heavy chain deficiency</oboInOwl:hasRelatedSynonym>
        <rdfs:comment>See https://github.com/NCI-Thesaurus/thesaurus-obo-edition/issues/18</rdfs:comment>
        <oboInOwl:hasRelatedSynonym>immunoglobulin heavy chain deletion</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>MONDO:0002211</oboInOwl:id>
        <ns4:IAO_0000115>A broad classification of disorders where circulating numbers of B lymphocytes are decreased or ineffective. Complement components and the production of antibodies may also be deficient.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>MEDGEN:340780</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>deficiency of humoral immunity</oboInOwl:hasExactSynonym>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/340780"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C1855067"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_2115"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C4799"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0003778 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0003778">
        <rdfs:label>inborn error of immunity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0004805 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0004805">
        <rdfs:label>leukocyte disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0021094 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0021094">
        <rdfs:label>immunodeficiency disease</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



