disease disrupts disease causes disruption of myelin maintenance demyelinating disease https://www.malacards.org/card/demyelinating_disease demyelinating disorder MESH:D003711 MONDO:0002562 NCIT:C34527 UMLS:C0011303 A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase traveling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others. MEDGEN:4189 DOID:3213 neurodegenerative disease disorder of development or morphogenesis