disease has location anal Paget disease https://www.malacards.org/card/anal_pagets_disease A slowly spreading, erythematous eczematoid plaque in the anal region. Histologically, the basal part or whole thickness of the squamous epithelium is infiltrated by large cells with abundant pale cytoplasm and large nuclei. Half of the cases are associated with an internal malignancy, most often a colorectal adenocarcinoma. The other half of the cases, have a high local recurrence rate and they may become invasive (WHO). Paget's disease of the anus Paget disease of the anus anal Paget's disease anus mammary Paget's disease NCIT:C5598 UMLS:C1332274 Paget's disease of anus GARD:0023203 MONDO:0002651 MEDGEN:233981 anus Paget disease DOID:3446 anal Paget disease anus adenocarcinoma extramammary Paget disease Paget disease anus