dysgerminoma https://www.malacards.org/card/dysgerminoma dysgerminoma (disease) A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage. GARD:0023323 MESH:D004407 MEDGEN:41680 ICDO:9060/3 NCIT:C2996 dysgerminoma (disease) DOID:4441 MONDO:0003002 NANDO:2200066 icd11.foundation:817547820 HP:0100621 dysgerminoma, malignant dysgerminoma UMLS:C0013377 malignant germ cell tumor germinomatous germ cell tumor