striatonigral degeneration https://www.malacards.org/card/striatonigral_degeneration MEDGEN:124366 ICD10CM:G23.2 MESH:D020955 icd11.foundation:195535779 ICD9:333.0 NCIT:C125695 MONDO:0003122 A progressive neurodegenerative disorder caused by a disruption in the connection between the striatum and the substantia nigra. It is a type of multiple system atrophy (MSA). Signs and symptoms include rigidity, instability, impaired speech, and slow movements. DOID:4751 OMIMPS:271930 SCTID:29618004 GARD:0023374 UMLS:C0270733 multiple system atrophy inborn errors of metabolism inherited neurodegenerative disorder