disease arises from structure disease arises from alteration in structure bladder urachal carcinoma https://www.malacards.org/card/bladder_urachal_carcinoma Orphanet:695020 Urachal cancer is a type of bladder cancer, making up less than 1% of all bladder cancers. The urachus is a structure normally only present during development in the womb that connects the bellybutton and the bladder. This connection normally disappears before birth, but in some people remains. Urachalcancers are usually diagnosed in adults in their 50's and 60's and may develop at the dome or anterior wall of the bladder, along the midline of the body (including the belly button), and between the pubis symphasis and the bladder.Most urachal cancersare adenocarcinomas (cancers that develop from gland cells).Others may besarcomas (which develop from connective tissue -such as leiomyosarcoma, rhabdomyosarcoma, and malignant fibrous histiocytoma), small cell carcinomas, transitional cell cancer, and mixed neoplasias. Most individuals with urachal cancer have symptoms of with hematuria (blood in urine). Other symptoms may include abdominal pain, a palpable abdominal mass, mucinuria, and bacteriuria. Treatment usually involved surgery to remove the cancer. MONDO:0003715 bladder urachal cancer MEDGEN:419015 NCIT:C39842 UMLS:C2931202 ONCOTREE:URCA DOID:5958 MESH:C536475 bladder urachal carcinoma urachal carcinoma urinary bladder carcinoma urachus epithelium