B cell deficiency selective immunoglobulin deficiency disease https://www.malacards.org/card/selective_immunoglobulin_deficiency_disease NCIT:C27870 A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of one of the five immunoglobulin classes. Deficiencies of immunoglobulins present variably according to isotype. Selective deficiencies may be caused by decreased or inefficient production from progenitor B cells without any corresponding decreases in the other isotypes. The clinical course and prognosis is dependent upon the severity of the selective deficiency and associated morbidity. MEDGEN:235584 selective Immunoglobulin isotype deficiency DOID:6025 GARD:0023643 UMLS:C1335942 MONDO:0003739