disease has location seminoma extragonadal seminoma mediastinum seminoma https://www.malacards.org/card/mediastinum_seminoma MEDGEN:277355 mediastinum seminoma seminoma of the mediastinum An extragonadal malignant germ cell tumor that arises from the mediastinum. It is characterized by the presence of uniform cells with clear or eosinophilic cytoplasm, round nucleus with one or more nucleoli, and distinct cellular borders. It usually arises from the anterior mediastinum. It may present with respiratory distress, chest pain, or superior vena cava syndrome or it may be asymptomatic, with the tumor detected on routine chest x-ray. The prognosis of mediastinal pure seminomas is favorable compared to the mediastinal non-seminomatous malignant germ cell tumors. DOID:6249 MONDO:0003826 UMLS:C1334680 GARD:0023685 seminoma of mediastinum NCIT:C6812 mediastinal seminoma mediastinal malignant germ cell tumor mediastinum