malignant exocrine pancreas neoplasm pancreatic intraductal papillary-mucinous neoplasm GARD:0027673 MONDO:0004286 pancreatic intraductal papillary-mucinous neoplasm ONCOTREE:IPMN DOID:7575 IPMN NCIT:C38342 A usually slow-growing epithelial neoplasm with ductal differentiation that arises from the exocrine pancreas and grows mostly within the pancreatic ducts. Grossly, it is characterized by the presence of intraductal masses. Morphologically, there is proliferation of mucin-producing cells within the pancreatic ducts, intraductal accumulation of mucin, and a papillary growth pattern. It may be associated with the presence of an invasive carcinoma. It usually occurs in older patients. Signs and symptoms include epigastric pain, weight loss, jaundice, chronic pancreatitis, and diabetes mellitus. MEDGEN:1373306 intraductal papillary mucinous neoplasm pancreatic intraductal papillary-mucinous tumor pancreatic IPMN pancreatic intraductal papillary-mucinous tumour UMLS:C4511687