pediatric osteosarcoma conventional osteosarcoma childhood intracortical osteosarcoma https://www.malacards.org/card/childhood_intracortical_osteosarcoma NCIT:C6590 childhood conventional osteosarcoma A high grade malignant bone-forming mesenchymal neoplasm that produces osteoid and occurs in childhood. It arises from the medullary portion of the bone. It affects the long bones, and most commonly, the distal femur, proximal tibia, and proximal humerus. Pain with or without a palpable mass is the most common clinical presentation. It usually has an aggressive growth and may metastasize through the hematogenous route. The lung is the most frequent site of metastasis. UMLS:C1332974 MEDGEN:232350 DOID:7612 childhood intracortical osteosarcoma GARD:0023922 MONDO:0004306