has characteristic has characteristic disease has location Adult onset spinal cord glioma adult spinal cord glioblastoma https://github.com/monarch-initiative/mondo/issues/9285 https://www.malacards.org/card/adult_spinal_cord_glioblastoma_multiforme NCIT:C27183 A rare spinal tumor which is highly malignant and tends to be locally invasive of surrounding neural tissue. The tumor also tends to spread throughout the neuroaxis and is often rapidly progressive. Histologically the tumors are highly cellular with nuclear and cellular pleomorphism, endothelial proliferation, mitotic figures, and, often, necrosis. This tumor has a relatively poor prognosis. Clinical features may include pain followed by rapidly progressive neurologic deficits such as extremity weakness, sensory changes, spasticity, and incontinence. (From Innocenzi et al., Clin Neurol Neurosurg 1997 Feb;99(1):1-5) MONDO:0004363 MEDGEN:107849 adult spinal cord glioblastoma UMLS:C0559185 SCTID:276829003 DOID:7806 GARD:0023957 adult spinal cord glioblastoma multiforme glioblastoma adult glioblastoma spinal cord