disease arises from feature disease has basis in feature benign spiradenoma malignant spiradenoma https://www.malacards.org/card/malignant_spiradenoma A very rare, aggressive carcinoma of the sweat glands arising from malignant transformation of a long standing spiradenoma. It usually grows in the upper extremities, lower extremities, trunk, and head and neck. It has the tendency to recur and metastasize most often to the lymph nodes, bones, and lungs. NCIT:C5117 spiradenoma, malignant GARD:0010466 Spiradenocarcinoma UMLS:C1266063 SCTID:403942003 malignant eccrine spiradenoma (morphologic abnormality) DOID:7960 MEDGEN:266097 malignant eccrine spiradenoma ICDO:8403/3 malignant spiradenoma MONDO:0004412 eccrine carcinoma secondary neoplasm