disease has location esophageal disorder esophageal leukoplakia https://www.malacards.org/card/esophageal_leukoplakia esophageal leukoplakia leukoplakia of esophagus UMLS:C0267095 esophageal leukoplakia (disease) leukoplakia of the esophagus oesophagus leukoplakia ICD9:530.83 HP:0012859 DOID:9021 leukoplakia of oesophagus A rare condition that usually affects the middle-to-distal esophagus in middle-aged and elderly people. There is usually a history of tobacco smoking or alcohol intake. Dysphagia is the presenting symptom. Morphologically, the lesions are well-demarcated and are characterized by epithelial hyperplasia, thickened basal layer, prominent granular cell layer, and hyperorthokeratosis. In a minority of patients this condition is associated with adjacent high-grade squamous dysplasia and/or squamous cell carcinoma. MONDO:0004697 SCTID:89057003 esophageal epidermoid metaplasia leukoplakia of the oesophagus esophagus leukoplakia NCIT:C3953 esophageal leukoplakia (disease) MEDGEN:75628 leukoplakia esophagus