syndromic disease central sleep apnea syndrome https://www.malacards.org/card/central_sleep_apnea central Apneas A broad classification of disorders which includes 6 subtypes (primary central sleep apnea, central sleep apnea due to Cheyne-Stokes breathing pattern, central sleep apnea due to medical condition not Cheyne-Stokes, central sleep apnea due to high-altitude periodic breathing, central sleep apnea due to drug or substance and primary sleep apnea of infancy) that are each characterized by interruptions in breathing while asleep. It is caused by improper signaling from the brainstem to respiratory muscles and is triggered by either hypoventilation or hyperventilation. In adults, this disorder may arise following a stroke, congestive heart failure, trauma, infection or the use of narcotic medications. It is more common in older males and may present as a co-morbid condition to obesity. Clinical signs include snoring, insomnia or hypersomnia, difficulty concentrating and fatigue. Recurrent episodes of hypoxia/hypoxemia have long-term detrimental effects on cardiovascular health. Apneas, central sleep central sleep apnea, secondary central sleep disordered breathing primary central sleep apnea DOID:9220 UMLS:C3887547 sleep-disordered Breathings, central hypoventilation, central alveolar central alveolar hypoventilation syndrome NCIT:C27169 MONDO:0004731 breathing, central sleep-disordered MESH:D020182 central sleep Apneas Apneas, central SCTID:27405005 central apnea alveolar hypoventilations, central hypoventilations, central alveolar MEDGEN:854402 sleep-disordered breathing, central apnea, central sleep alveolar hypoventilation, central central sleep-disordered breathing Breathings, central sleep-disordered secondary central sleep apnea apnea, sleep, central ondine syndrome sleep disordered breathing, central sleep apnea, lethal central central alveolar hypoventilation central sleep apnea, primary central sleep-disordered Breathings sleep Apneas, central apnea, central central sleep apnea central sleep apnea syndrome sleep apnea syndrome