disease has basis in disruption of disease caused by disruption of disease has location disaccharide metabolic process disease intestinal disaccharidase deficiency https://www.malacards.org/card/intestinal_disaccharidase_deficiency UMLS:C0699848 DOID:9868 EFO:1000060 SCTID:22169002 MONDO:0006062 intestinal disaccharidase deficiency and disaccharide malabsorption ICD9:271.3 MONDO:0004905 NCIT:C34731 Inherited or acquired disorders of sugar metabolism. Deficiencies of lactase, maltase or sucrase-isomaltase usually occur irreversibly and independent of one another. Congenital deficiencies are rare whereas acquired deficiencies are more common and may be seen following intestinal mucosal brush-border injury. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following dietary intake of lactose, maltose or sucrose. The clinical course leads to malabsorption of disaccharides which has implications for normal growth and development if manifested at an early age. MEDGEN:675093 inborn carbohydrate metabolic disorder malabsorption syndrome carbohydrate metabolism disease intestine digestive system