disease has location oral cavity squamous cell carcinoma https://rarediseases.info.nih.gov/diseases/7263/oral-squamous-cell-carcinoma https://www.malacards.org/card/oral_squamous_cell_carcinoma https://www.malacards.org/card/squamous_cell_carcinoma_head_and_neck UMLS:C0585362 DOID:0050866 OCSC Orphanet:502363 mouth scc scc of oral cavity A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status. SCTID:307502000 scc of the oral cavity squamous cell carcinoma of the mouth scc of the mouth ONCOTREE:OCSC oral cavity squamous cell carcinoma oral cavity squamous cell cancer NCIT:C4833 oral cavity scc EFO:0000199 MEDGEN:108436 scc of mouth MONDO:0004958 squamous cell carcinoma of mouth oral squamous cell carcinoma GARD:0017932 mouth squamous cell carcinoma squamous cell carcinoma of oral cavity squamous cell carcinoma of the oral cavity squamous cell carcinoma lip and oral cavity squamous cell carcinoma oral cavity carcinoma mouth