disease has location adenocarcinoma colorectal adenocarcinoma https://www.malacards.org/card/colorectal_adenocarcinoma https://www.malacards.org/card/large_intestine_adenocarcinoma Editor note: we follow NCIT in treating colorectal and large intestine as equivalent adenocarcinoma of large intestine ONCOTREE:COADREAD colorectal (colon or rectal) adenocarcinoma EFO:0000365 colorectum adenocarcinoma large bowel adenocarcinoma DOID:0050861 colorectal adenocarcinoma UMLS:C1319315 SCTID:408645001 MONDO:0005008 adenocarcinoma of the large bowel NCIT:C5105 adenocarcinoma of the large intestine MEDGEN:230816 The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. DOID:0050913 adenocarcinoma of large bowel colorectal carcinoma colorectum