respiratory system disorder skin disorder systemic sclerosis https://github.com/monarch-initiative/mondo/issues/9097 https://www.malacards.org/card/scleroderma_familial_progressive https://www.malacards.org/card/systemic_scleroderma Scleroderma Scleroderma, diffuse DOID:418 icd11.foundation:1084365812 systemic Scleroderma Orphanet:90291 Systemic Scleroderma UMLS:C0036421 SSc diffuse sclerosis MEDGEN:19897 NANDO:2200429 ICD10CM:M34 diffuse Scleroderma NCIT:C72070 PSS (progressive systemic sclerosis) A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension. Scleroderma (& [systemic sclerosis]) Scleroderma, systemic GARD:0009748 systemic sclerosis systemic scleroderma MONDO:0005100 ICD10WHO:M34 NANDO:1200277 ICD9:710.1 MedDRA:10042953 SSc, diffuse sclerosis EFO:0000717 SCTID:89155008 NORD:2007 MESH:D012595 non-familial restrictive cardiomyopathy scleroderma obsolete secondary glomerular disease