liposarcoma well-differentiated liposarcoma https://www.malacards.org/card/well_differentiated_liposarcoma ALT well differentiated liposarcoma of deep soft tissue well differentiated liposarcoma ICDO:8851/3 WDLS MEDGEN:237164 atypical lipoma GARD:0019721 MONDO:0005103 UMLS:C1370889 EFO:0000736 atypical lipomatous tumor NCIT:C4250 ONCOTREE:WDLS well-differentiated liposarcoma atypical lipomatous tumour A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation. Orphanet:99971