melanoma https://www.malacards.org/card/melanoma ICDO:8720/3 MEDGEN:9944 MONDO:0005105 A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain. ONCOTREE:MEL EFO:0000756 NCIT:C3224 SCTID:372244006 NANDO:2200077 Orphanet:411533 MESH:D008545 DOID:1909 malignant melanoma melanoma (disease) HP:0002861 melanoma UMLS:C0025202 melanoma (disease) melanoma, malignant neuroendocrine neoplasm melanocytic neoplasm