atopic IgE-mediated allergic disorder SCTID:115665000 MONDO:0005202 Editor notes: this is a finding in NCIT ICD9:995.3 MEDGEN:739536 A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms. UMLS:C1706410 EFO:0002686 allergic disease