disease has feature disease has infectious agent Anemia Headache trypanosomiasis anemia human African trypanosomiasis https://www.malacards.org/card/sleeping_sickness Africam sleeping sickness MEDGEN:21714 A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death. ICD9:086.5 MedDRA:10001461 MESH:D014353 Orphanet:3385 EFO:0005225 SCTID:27031003 UMLS:C0041228 African trypanosomiasis MONDO:0005459 NCIT:C84541 GARD:0007826 MONDO:0018073 DOID:10112 sleeping sickness vector-borne disease Trypanosoma brucei