extragonadal nonseminomatous germ cell tumor yolk sac tumor https://www.malacards.org/card/endodermal_sinus_tumor MEDGEN:41782 NCIT:C3011 yolk sac tumor MedDRA:10048251 yolk Sac tumor site unspecified endodermal sinus tumor ONCOTREE:BYST A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum. hepatoid yolk sac tumor yolk SAC tumor, malignant NANDO:2200069 EFO:0007252 UMLS:C0014145 SCTID:404081005 yolk Sac tumour site unspecified ICDO:9071/3 yolk Sac tumor yolk Sac neoplasm Orphanet:876 MONDO:0005744 GARD:0000348 endodermal sinus neoplasm DOID:1911 infantile embryonal carcinoma