disease arises from structure disease arises from alteration in structure spindle cell sarcoma intimal sarcoma MEDGEN:317791 MONDO:0006255 EFO:1000305 ONCOTREE:INTS GARD:0024348 NCIT:C53677 INTS UMLS:C1708550 A malignant neoplasm arising from the large blood vessels. It is characterized by the presence of tumor cells that grow within the lumen of the blood vessels. The intraluminal tumor growth may result in vascular obstruction and spread of tumor emboli to peripheral organs. The prognosis is usually poor. soft tissue sarcoma blood vessel