<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0006266"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/mondo#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MONDO_0006055 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0006055">
        <rdfs:label>sex cord-stromal tumor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0006266 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0006266">
        <rdfs:label>Leydig cell tumor</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0006055"/>
        <ns4:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/leydig_cell_tumor</ns4:curated_content_resource>
        <oboInOwl:hasExactSynonym>Leydig cell tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MONDO:0006266</oboInOwl:id>
        <oboInOwl:hasDbXref>DOID:2696</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:8650/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D007984</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>interstitial cell tumor</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MEDGEN:9747</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>Leydig cell neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>interstitial cell tumour</oboInOwl:hasExactSynonym>
        <rdfs:comment>Editor notes: Adding an axiom to this to localize to leydig cell entails equivalence with testicular leydig cell tumor</rdfs:comment>
        <oboInOwl:hasDbXref>UMLS:C0023601</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:1000321</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>interstitial cell neoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIT:C3188</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Leydig cell tumor, undetermined</oboInOwl:hasRelatedSynonym>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/9747"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/mesh/D007984"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0023601"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_2696"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C3188"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <skos:exactMatch rdf:resource="http://www.ebi.ac.uk/efo/EFO_1000321"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



