primary cutaneous diffuse large B-cell lymphoma, Leg type https://www.malacards.org/card/primary_cutaneous_diffuse_large_b_cell_lymphoma_leg_type An aggressive primary cutaneous B-cell lymphoma, usually involving the lower leg. It is composed of a generally monotonous proliferation of immunoblasts, or less frequently centroblasts, with few admixed reactive cells. This type of lymphoma occurs most often in elderly women who present with rapidly growing tumors, usually on one or both legs. Dissemination to extracutaneous sites is frequent. Treatment with combination chemotherapy is usually required. GARD:0020160 NCIT:C45194 UMLS:C1709656 primary cutaneous diffuse large B-cell lymphoma, Leg type ICDO:9680/3 EFO:1000490 PCDLBCL,LT icd11.foundation:1418101362 MEDGEN:311155 Orphanet:178544 MONDO:0006383 diffuse large B-cell lymphoma