osteoarthritis osteoarthritis, spine MONDO:0006630 MEDGEN:389941 EFO:1000787 MESH:D055013 UMLS:C2350242 SCTID:8847002 A degenerative joint disease involving the spine. It is characterized by progressive deterioration of the spinal articular cartilage (cartilage, articular), usually with hardening of the subchondral bone and outgrowth of bone spurs (osteophyte).