breast adenocarcinoma invasive breast carcinoma inflammatory breast carcinoma https://www.malacards.org/card/inflammatory_breast_carcinoma DOID:6263 NCIT:C4001 inflammatory carcinoma of breast MESH:D058922 SCTID:254840009 MedDRA:10006205 MEDGEN:75841 UMLS:C0278601 GARD:0006784 inflammatory breast carcinoma ONCOTREE:IBC MONDO:0006804 IBC ICDO:8530/3 inflammatory carcinoma of the breast Orphanet:694963 mastitis carcinomatosa mastitis Carcinomatosa EFO:1000984 inflammatory breast cancer breast cancer, inflammatory An advanced, invasive breast adenocarcinoma characterized by the presence of distinct changes in the overlying skin. These changes include diffuse erythema, edema, peau d'orange (skin of an orange) appearance, tenderness, induration, warmth, enlargement, and in some cases a palpable mass. The skin changes are the consequence of lymphatic obstruction from the underlying invasive breast adenocarcinoma. Microscopically, the dermal lymphatics show prominent infiltration by malignant cells. The invasive breast adenocarcinoma is usually of ductal, NOS type. There is not significant inflammatory cell infiltrate present, despite the name of this carcinoma.