disease arises from feature disease has basis in feature movement disorder prion disease neurodegenerative disease kuru https://rarediseases.info.nih.gov/diseases/7617/kuru https://www.malacards.org/card/kuru icd11.foundation:553889510 EFO:1001008 A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) MedDRA:10023497 MESH:D007729 ICD10CM:A81.81 GARD:0007617 MONDO:0006825 Orphanet:454745 ICD9:046.0 SCTID:86188000 DOID:648 MEDGEN:9653 UMLS:C0022802 human prion disease