syphilis syphilitic aortitis UMLS:C0003511 MEDGEN:364 icd11.foundation:921262131 ICD10CM:A52.02 ICD9:093.1 MedDRA:10042900 SCTID:20735004 GARD:0027769 EFO:1001206 MONDO:0006992 Cardiovascular manifestations of syphilis, an infection of treponema pallidum. In the late stage of syphilis, sometimes 20-30 years after the initial infection, damages are often seen in the blood vessels including the aorta and the aortic valve. Clinical signs include syphilitic aortitis, aortic insufficiency, or aortic aneurysm.