kidney failure uremia https://www.malacards.org/card/uremia MedDRA:10046369 EFO:1001226 MESH:D014511 MONDO:0007008 DOID:4676 A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of renal insufficiency. Most uremic toxins are end products of protein or nitrogen catabolism, such as urea or creatinine. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms. MEDGEN:12008 SCTID:44730006 uremia of renal origin UMLS:C0041948