brain disorder Wernicke encephalopathy https://www.malacards.org/card/wernicke_encephalopathy DOID:2384 Wernicke's encephalopathy MONDO:0007020 SCTID:21007002 Orphanet:97354 MEDGEN:53073 dementia due to thiamine deficiency An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. thiamine deficiency and chronic alcoholism are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to korsakoff syndrome. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3) icd11.foundation:1360335041 ICD9:265.1 ICD10CM:E51.2 UMLS:C0043121 MESH:D014899 alcohol-related disorders