has material basis in germline mutation in APOE Alzheimer disease 2 https://github.com/monarch-initiative/mondo/issues/3947 https://www.malacards.org/card/alzheimer_disease_2_2 An Alzheimer's disease that is characterized by an association of the apolipoprotein E E4 allele. AD2 MEDGEN:400197 OMIM:104310 Alzheimer disease type 2 DOID:0110035 LOFAD MESH:C536595 late onset Alzheimer disease UMLS:C1863051 Alzheimer disease associated with APOE E4 Alzheimer disease associated with APOE4 MONDO:0007089 late-onset familial alzheimer disease late onset familial Alzheimer disease Alzheimer disease 2 Alzheimer's disease type 2 Alzheimer's disease 2 early-onset autosomal dominant Alzheimer disease familial Alzheimer disease