Ascher syndrome https://rarediseases.info.nih.gov/diseases/201/ascher-syndrome https://www.malacards.org/card/blepharochalasis_and_double_lip icd11.foundation:1063203220 Ascher's syndrome ICD9:246.8 MESH:C562742 SCTID:28599006 MEDGEN:137910 Double upper lip, blepharochalasis and enlargement of the thyroid blepharochalasis and Double type lip MONDO:0007198 Orphanet:1253 UMLS:C0339085 Ascher syndrome OMIM:109900 Ascher syndrome is a very rare syndrome characterized by a combination of blepharochalasis, double lip, and non-toxic thyroid enlargement (seen in 10-50% of cases), although the occurrence of all three signs at presentation is uncommon. Hypertrophy of the mucosal zone of the lip with persistence of the horizontal sulcus between cutaneous and mucosal zones gives an appearance of double lip, with the upper lip being frequently involved. Blepharochalasis, or episodic edema of eyelid, appears around puberty, is present in 80% of cases, is usually bilateral, and can rarely lead to vision impairment and other ocular complications. Most cases are sporadic, but familial cases (with a possible autosomal dominant inheritance) have also been reported. blepharochalasis-double lip syndrome ICD9:374.89 GARD:0000201 blepharochalasis - double lip blepharochalasis and double lip multiple congenital anomalies/dysmorphic syndrome without intellectual disability