has material basis in germline mutation in disease has feature LMNA syndromic disease cardiomyopathy dilated cardiomyopathy 1A https://github.com/monarch-initiative/mondo/issues/7693 https://rarediseases.info.nih.gov/diseases/1104/cardiomyopathy-dilated-with-conduction-defect-type-1 https://www.malacards.org/card/cardiomyopathy_dilated_1a cardiomyopathy, dilated, type 1A Orphanet:300751 dilated cardiomyopathy 1A MEDGEN:1875382 icd11.foundation:884022112 Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase. OMIM:115200 LMNA familial isolated dilated cardiomyopathy GARD:0018615 DOID:0110425 cardiomyopathy dilated with conduction defect type 1 familial isolated dilated cardiomyopathy caused by mutation in LMNA MONDO:0007269 UMLS:C5979868 cardiomyopathy, dilated, 1A SCTID:766883006 dilated cardiomyopathy type 1A CDCD1 familial dilated cardiomyopathy with conduction defect due to LMNA mutation familial isolated dilated cardiomyopathy