has characteristic has characteristic has material basis in germline mutation in SDHB Autosomal dominant inheritance autosomal dominant disease paraganglioma pheochromocytoma/paraganglioma syndrome 4 https://github.com/monarch-initiative/mondo/issues/9178 https://rarediseases.info.nih.gov/diseases/10546/paragangliomas-4 https://www.malacards.org/card/pheochromocytoma_paraganglioma_syndrome_4 SDHB paraganglioma pheochromocytoma, extraadrenal and cervical paraganglioma paragangliomas type 4 An autosomal dominant tumor predisposition disorder caused by pathogenic variants in the SDHB gene, characterized by an increased risk of paraganglioma and pheochromocytoma, as well as an increased risk of renal cell carcinoma and gastrointestinal stromal tumors (GIST). SDHB-related tumor predisposition paraganglioma caused by mutation in SDHB MONDO:0007273 pheochromocytoma/paraganglioma syndrome 4 PGL4 OMIM:115310 MEDGEN:349380 UMLS:C1861848 GARD:0010546 DOID:0061219 SDHB-related hereditary paraganglioma-pheochromocytoma syndrome paragangliomas 4 carotid body tumours and multiple extraadrenal Pheochromocytomas hereditary neoplastic syndrome hereditary pheochromocytoma-paraganglioma