syndromic disease self-limited epilepsy with centrotemporal spikes https://github.com/monarch-initiative/mondo/issues/2545 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/8490 https://github.com/monarch-initiative/mondo/issues/9285 https://rarediseases.info.nih.gov/diseases/10287/benign-rolandic-epilepsy-bre https://www.epilepsydiagnosis.org/syndrome/ects-overview.html https://www.malacards.org/card/benign_epilepsy_with_centrotemporal_spikes https://www.malacards.org/card/centralopathic_epilepsy https://www.malacards.org/card/self_limited_epilepsy_with_centrotemporal_spikes icd11.foundation:1046279423 A childhood-onset epilepsy syndrome that is characterized by onset of seizures between 3 and 14 years (peak 8-9 years) that usually resolve by age 13 years, but can occasionally occur up to age 18 years of age. Both sexes are affected. Antecedent, birth and neonatal history is normal. A history of febrile seizure (in 5-15%) may be seen. A history of Panayiotopoulos syndrome may be present in a very small number of cases. Neurological exam and head size is normal. Development and cognition prior to onset of seizures is normal. During the course of the active epilepsy, behavioral and neuropsychological deficits may be found, particularly in language and executive functioning. These deficits improve when seizures remit. GARD:0010287 benign Rolandic epilepsy MEDGEN:138210 Orphanet:1945 benign childhood epilepsy with centrotemporal spikes BECTS SCTID:44145005 benign epilepsy of childhood with centrotemporal spikes (BECCT) benign Rolandic epilepsy of childhood (BREC) benign epilepsy with centrotemporal spikes childhood epilepsy with centrotemporal spikes centralopathic epilepsy benign familial epilepsy of childhood with rolandic spikes centrotemporal epilepsy NCIT:C116538 benign Rolandic epilepsy (BRE) BRE ICD9:345.80 centrotemporal epilepsy, isolated cases Rolandic epilepsy DOID:3329 OMIM:117100 temporal-central focal epilepsy Childhood epilepsy with centrotemporal spikes, atypical childhood epilepsy with centrotemporal spikes, epileptic encephalopathy with continuous spike-and-wave during sleep and Landau Kleffner syndrome are syndromes that have in common certain EEG features, with variable severity of focal seizures and neurocognitive impairment. They may be considered as a spectrum, an individual child may transition from one of these syndromes to another over time. MONDO:0007295 benign epilepsy of childhood with centrotemporal spikes BECRS BCECTS UMLS:C0376532 benign epilepsy with centro-temporal spikes (BECTS) Landau-Kleffner syndrome familial partial epilepsy childhood-onset self-limited focal epilepsy syndrome