autosomal dominant disease cleft lip Rapp-Hodgkin syndrome https://rarediseases.info.nih.gov/diseases/5690/rapp-hodgkin-syndrome https://www.malacards.org/card/rapp_hodgkin_syndrome GARD:0005690 Rapp-Hodgkin ectodermal dysplasia syndrome Orphanet:3022 MONDO:0007508 ectodermal dysplasia, anhidrotic, with cleft lip-palate RHS MEDGEN:315656 OMIM:129400 SCTID:7731005 UMLS:C1785148 MESH:C535289 Rapp-Hodgkin syndrome A form of ectodermal dysplasia characterized by the association of anhidrotic ectodermal dysplasia with cleft lip/palate. icd11.foundation:1455333054 DOID:0060330 Rapp-Hodgkin syndrome has signs and symptoms that overlap considerably with those of ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome. These two syndromes were classified as separate disorders until it was discovered that they both result from mutations in the same part of the same gene. Most researchers now consider Rapp-Hodgkin syndrome and AEC syndrome to be part of the same disease spectrum OFC8, included cleft palate ectodermal dysplasia syndrome TP63-related ectodermal dysplasia spectrum with limb and orofacial malformations