autosomal dominant disease Flynn-Aird syndrome https://rarediseases.info.nih.gov/diseases/2347/flynn-aird-syndrome https://www.malacards.org/card/flynn_aird_syndrome_2 MEDGEN:91009 Flynn-Aird syndrome MONDO:0007624 OMIM:136300 SCTID:239056006 MESH:C537066 GARD:0002347 Flynn-Aird syndrome is a neuroectodermal disorder involving the nervous, cutaneous, skeletal, and glandular systems. It has been described in 10 members from five generations of one family. Clinical manifestations include eye abnormalities (cataracts, retinitis pigmentosa, and myopia), sensorineural deafness, ataxia, peripheral neuritis, epilepsy, dementia, skin atrophy and striking dental caries. Patients also present with muscle wasting, joint stiffness and bone cysts. Flynn-Aird syndrome is transmitted as an autosomal dominant trait. It shows some similarities to the syndromes of Werner, Refsum and Cockayne. cataracts, retinitis pigmentosa, sensorineural hearing loss, ataxia, peripheral neuritis, epilepsy, dementia, skin atrophy, chronic ulceration, dental Flynn Aird syndrome UMLS:C0343108 Orphanet:2047 obsolete genetic nervous system disorder premature aging syndrome