heart-hand syndrome type 3 https://www.malacards.org/card/heart_hand_syndrome_spanish_type OMIM:140450 heart-limb syndrome type 3 upper limb malformations and congenital cardiac anomalies MONDO:0007702 MEDGEN:333883 icd11.foundation:1878745129 Orphanet:1342 heart-hand syndrome, Spanish type Heart-hand syndrome type 3 is a very rare heart-hand syndrome, described in three members of a Spanish family to date, which is characterized by a cardiac conduction defect (sick sinus, bundle-branch block) and brachydactyly, resembling brachydactyly type C of the hands, affecting principally the middle phalanges in conjunction with an extra ossicle on the proximal phalanx of both index fingers. Feet abnormalities are more subtle. Cardiomelic syndrome type 3 UMLS:C1841657 GARD:0002614 atriodigital dysplasia type 3 brachydactyly and intraventricular conduction defect MESH:C535853 SCTID:721013001 Holt-Oram syndrome