hereditary disease oculoauriculovertebral spectrum with radial defects https://github.com/monarch-initiative/mondo/issues/6751 https://github.com/monarch-initiative/mondo/issues/6877 https://www.malacards.org/card/hemifacial_microsomia_with_radial_defects Oculoauriculovertebral spectrum (OAVS) with radial defects is a rare branchial arches and limb primordia development disorder characterized by variable degrees of uni- or bilateral craniofacial malformation and radial defects that result in extremely variable phenotypic manifestations. Characteristic features include low postnatal weight, short stature, vertebral defects, hearing loss, and facial dysmorphism (incl. facial asymmetry, external, middle, and inner ear malformations, orofacial clefts, and mandibular hypoplasia). These features are invariably associated with radial defects, such as preaxial polydactyly, thumb and/or radius hypoplasia/agenesis, or triphalangeal thumb. Cardiac, pulmonary, renal, and central nervous system involvement has also been reported. OMIM:141400 Moeschler Clarren syndrome GARD:0003653 hemifacial microsomia-radial defects syndrome Moeschler-Clarren syndrome UMLS:C0220681 Orphanet:2549 SCTID:726722009 MONDO:0007712 MEDGEN:67392 microsomia hemifacial radial defects multiple congenital anomalies/dysmorphic syndrome without intellectual disability dysostosis