has material basis in germline mutation in MFN2 integumentary system benign neoplasm lipomatosis multiple symmetric lipomatosis https://rarediseases.info.nih.gov/diseases/6957/multiple-symmetric-lipomatosis https://www.malacards.org/card/lipomatosis_multiple_symmetric_with_or_without_axonal_peripheral_neuropathy https://www.malacards.org/card/multiple_symmetric_lipomatosis benign symmetrical lipomatosis familial symmetric lipomatosis SCTID:238902007 lipodystrophy, cephalothoracic Madelung's disease Madelung's Disease cephalothoracic lipodystrophy GARD:0006957 EFO:1000737 lipomatosis, familial benign cervical lipomatosis, multiple symmetric Launois-Bensaude syndrome multiple symmetrical lipomatosis MEDGEN:7349 MSL NCIT:C4392 multiple symmetric lipomatosis Madelung disease A rare subcutaneous tissue disease characterized by growth of symmetric non-encapsulated masses of adipose tissue mostly around the face and neck with variable clinical repercussions (e.g. reduced neck mobility, compression of respiratory structures). Launois-Bensaude lipomatosis OMIM:151800 NORD:1392 DOID:14116 Orphanet:2398 familial benign cervical lipomatosis MONDO:0007908 cervical symmetrical lipomatosis UMLS:C0023804 subcutaneous tissue disorder hereditary disorder of connective tissue