<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0008006"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/mondo#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#orphanet_rare"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#closeMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ncit_rare"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0004029 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0004029">
        <rdfs:label>disease has feature</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/HP_0000486 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000486">
        <rdfs:label>Strabismus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002098 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002098">
        <rdfs:label>facial nerve disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002254 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002254">
        <rdfs:label>syndromic disease</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0002320 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0002320">
        <rdfs:label>congenital nervous system disorder</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0008006 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0008006">
        <rdfs:label>Mobius syndrome</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002098"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002254"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0002320"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0015083"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0015160"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004029"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0000486"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns4:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/4521</ns4:IAO_0000233>
        <ns4:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/6751</ns4:IAO_0000233>
        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/moebius_syndrome</ns5:curated_content_resource>
        <oboInOwl:hasExactSynonym>Moebius syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>DOID:13501</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:157900</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>Moebius syndrome is a very rare congenital cranial dysinnervation disorder characterized by complete or incomplete facial paralysis in association with bilateral palsy of the abducens nerve causing impairment of ocular abduction. The syndrome also includes various other congenital anomalies.</ns4:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>absence or underdevelopment of the 6th and 7th cranial nerves</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Moebius syndrome, Isolated cases</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10030069</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NANDO:2200980</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:89444000</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0008006</oboInOwl:id>
        <oboInOwl:hasDbXref>GARD:0008549</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>oromandibular-limb hypogenesis spectrum</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MedDRA:10027789</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>MBS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>congenital oculofacial paralysis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>ICD9:759.89</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Moebius sequence</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MESH:D020331</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>congenital facial diplegia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIT:C84893</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:570</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NANDO:1200559</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Mobius syndrome</oboInOwl:hasExactSynonym>
        <rdfs:comment>This term&#39;s classification was reviewed in the context of the Strategic Refinement project (2023) and was determined to be excluded from the &#39;musculoskeletal system disorder&#39; (MONDO:0002081) ontology branch (https://orcid.org/0000-0001-9310-0163)</rdfs:comment>
        <oboInOwl:hasDbXref>NORD:1453</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>congenital facial diplegia syndrome</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>MEDGEN:66357</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Moebius Syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Möbius syndrome</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0221060</oboInOwl:hasDbXref>
        <skos:closeMatch rdf:resource="http://identifiers.org/meddra/10027789"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/meddra/10030069"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/66357"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/mesh/D020331"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/89444000"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0221060"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/DOID_13501"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C84893"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#doid_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ncit_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_disorder"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#orphanet_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_570"/>
        <skos:exactMatch rdf:resource="https://omim.org/entry/157900"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0015083 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0015083">
        <rdfs:label>nuclear oculomotor paralysis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0015160 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0015160">
        <rdfs:label>multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



