has material basis in germline mutation in MAFB multicentric carpo-tarsal osteolysis with or without nephropathy https://github.com/monarch-initiative/mondo/issues/4948 https://rarediseases.info.nih.gov/diseases/3818/multicentric-osteolysis-nephropathy https://www.malacards.org/card/multicentric_carpotarsal_osteolysis_syndrome SCTID:766992008 multicentric osteolysis nephropathy OMIM:166300 MEDGEN:436237 MONDO:0008152 idiopathic multicentric osteolysis with or without nephropathy Carnevale canun Mendoza syndrome multicentric carpotarsal osteolysis syndrome GARD:0003818 UMLS:C2674705 MESH:C567171 Idiopathic multicentric osteolysis is a very rare syndrome characterized by progressive loss of bone, usually the capsal and tarsal bones, resulting in deformity and disability, as well as chronic renal failure in many cases. The bone and renal disorders are sometimes associated with intellectual deficit and facial abnormalities. DOID:0111534 multicentric carpo-tarsal osteolysis with or without nephropathy MCTO Orphanet:2774 primary osteolysis